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應(yīng)用的篩選條件
本應(yīng)用簡(jiǎn)報(bào)為使用 XF 線粒體毒性檢測(cè)進(jìn)行化合物篩選和劑量響應(yīng)實(shí)驗(yàn)以及使用線粒 體毒性指標(biāo) (MTI) 解析結(jié)果數(shù)據(jù)提供了概念驗(yàn)證和示例。
| 英語 (美國(guó)) | 完整版（PDF） |
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概述安捷倫 Seahorse XF 細(xì)胞線粒體壓力測(cè)試和XF PMP工作流程如何應(yīng)用于線粒體和代謝靶點(diǎn)的識(shí)別研究。
An optimized Agilent XF 3D tissue workflow that allows for detection and quantitative assessment of energy metabolism in tissue materials is presented.
Agilent Seahorse XF 3D Mito Stress Test Tissue workflow quick start guide for use with the Agilent Seahorse XF Flex Analyzer and the Agilent Seahorse XF Flex 3D Capture Microplate-L.
Overview of the benefits of the Agilent Seahorse XF tissue metabolism workflow using the Seahorse XF Flex Analyzer and the Seahorse XF Flex 3D Capture Microplates-L
Demonstration of the wide range of metabolic rates that can be quantified on the Agilent Seahorse XF Flex analyzer through the use of different Seahorse XF microplates and in vitro differentiation of adipocytes.
Operating manual for the Agilent Seahorse XF Flex instrument.
Technical overview details use of the new Agilent Mito-rOCR assay, as innovative solution to assess mitochondrial respiration by relative oxygen consumption rate (rOCR) measurements using a fluorescence plate reader.
Research highlight confirming the critical role of metabolic fitness in CAR-NK cells and its importance to achieve superior clinical outcomes in immunotherapy.
A protocol for mitocondrial isolation and oxygen consumption analysis using the Agilent MitoXpress Xtra oxygen consumption assay.
This document is an information guide and checklist prepared for you that outlines the supplies, space, and utility requirements for the system set up in your lab.
This application note introduces a workflow that uses the XF Real-Time ATP rate assay data for identifying metabolic modulator and drug targets.
A demonstration of combining microelectrode-based iPS cardiomyocyte contractility measurements with microplate-based bioenergetics assessment to characterize cellular responses to drug treatment.
Characterize metabolic functionality of adipocytes differentiated from the pre-adipocyte 3Y3-L1 cell culture line using the Agilent Seahorse XF/XFe Analyzer.
Two workflows using MitoXpress Xtra and pH-Xtra probes to investigate cell metabolism in intact RAFT 3D collagen structures on fluorescent plate readers.
User guide for the MitoXpress Xtra Oxygen Consumption Assay kit. Includes workflow, plate reader-, storage conditions and signal optimization instructions.
A demonstration of the performance of the Agilent MitoXpress Xtra oxygen consumption assay for identifying drug induced mitocondrial toxicity.
Screening for Drug-Induced Mitochondrial Dysfunction Using MitoXpress Xtra on Isolated Mitochondria
Correlating Microbial Proliferation with Antibiotic Resistance using the MitoXpress Xtra Oxygen Consumption Assay
Protocol to assess primary whole islet bioenergetics in vitro using the Agilent Seahorse XF24 Islet Capture Microplate.