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Integrating cell analytics and feedback control to optimize T cell differentiation during ex vivo expansion in bioreactor (PDF)

This poster reveals to optimize T-cell differentiation in bioreactors using integrated Agilent cell analytics and feedback control to enhance CAR T-cell therapyproduction.

文件出版號(hào): Cyto 2025 #66
創(chuàng)建日期: 05 六月 2025
460 KB
PDF

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Changes in CAR T-cells manufacturing conditions yield to distinct T cell differentiation states, metabolic poise, and cytotoxic function (PDF)

CAR T-cell manufacturing conditions are critical to differentiation, metabolic fitness, and cytotoxic function, enhancing therapy efficacy and production efficiency.

文件出版號(hào): Cyto 2025
創(chuàng)建日期: 05 六月 2025
537 KB
PDF

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Chronic anti-CD3/CD28 stimulation during cell expansion generates exhausted T cells with a distinct metabolic and cytotoxic phenotype (PDF)

AACR 2025 poster: Chronic anti-CD3/CD28 stimulation during cell expansion generates exhausted T cells with a distinct metabolic and cytotoxic phenotype

文件出版號(hào): AACR #4856
創(chuàng)建日期: 25 四月 2025
475 KB
PDF

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In-Process Assessment of Critical Process Parameters Impacting CAR T Cell Potency, Metabolic Fitness and Phenotype (PDF)

we demonstrated consistent production of CAR T-cells using the functionally closed and automated cell manufacturing Lonza Cocoon platform, using a novelcombination of cell analysis parameters obtained from an Agilent xCELLigence RTCA system, a...

文件出版號(hào): #149
創(chuàng)建日期: 17 三月 2025
375 KB
PDF