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Active solvent modulation provides a valve-based approach to address incompatibilities between the first and second dimension solvent systems in 2D-LC.
2D-LC/MS/MS analysis of drugs and their metabolites in a pharmacokinetic study, eliminating coelution and the risk of cross-talk for for a complex sample
Direct 2D-LC analysis of oligonucleotides in solution with high salt content, with online desalting in the first dimension and IP-RPLC in the second dimension.
Method development of chiral screening with the Agilent 1260 Infinity II SFC/UHPLC Hybrid System and selected Agilent InfinityLab Poroshell 120 chiral columns.
Describes the use of the Agilent ChemStation Method Scouting Wizard in method development to separate and detect active compounds using SFC and TOF MS.
Quantitative determination of fat- and water-soluble vitamins using a 1260 Infinity II SFC/UHPLC Hybrid System with a 6470A Triple Quadrupole LC/MS System
Universal method development for various HPLC systems using the Agilent 1290 Infinity II Method Development Solution with Intelligent System Emulation Technology