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A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS
The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
LC/MS based characterization workflow of the GLP-1 therapeutic peptide liraglutide and its impurities using the 1290 Infinity II LC and 6545XT AdvanceBio LC/Q-TOF.
In the current study, We present a solid method for peptide quantification using capillary LC-MS/MS, emphasizing three key analytical parameters: (1) limit of detection (LOD) and limit of quantification (LOQ), (2) linear range for multiple peptides,...