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Oligonucleotide analysis with ion-pairing-free reversed phase method and TOF LC/MS
Direct 2D-LC analysis of oligonucleotides in solution with high salt content, with online desalting in the first dimension and IP-RPLC in the second dimension.
This user guide describes how to calculate the amount of PL-SAX media needed to pack a column. It briefly describes best practices for loading the column.
Competitive comparison from analytical to semipreparative purification of synthetic oligonucleotides.
From analytical to preparative scale, Agilent AdvanceBio Oligonucleotide columns, software, and instrumentation pair seamlessly to minimize method optimization and downtime.
This poster covers columns for oligonucleotide chromatography, from siRNA/ASO to mRNA.
AdvanceBio superficially porous columns for excellent performance and resolution for semi-prep purification of synthetic oligos without compromising column loading.
In this application note, we explore some of the key parameters when comparing different column chemistries using ion-pair reversed-phase (IP-RP) separation of Semaglutide.
Consumables workflow ordering guide for oligonucleotide purification using ion pair reversed-phase liquid chromatography.
Molecular weight confirmation and simple characterization workflows for synthetic oligos with Agilent LC/MSD XT and MS Spectral Deconvolution feature in OpenLab CDS 2.8.
This user guide compendium summarizes the different types of LC guard columns and how to install them.
Polymeric particles, such as PLRP-S and PL-SAX, are ideal for analyzing and purifying oligonucleotides. Because these materials are thermally and chemically stable, they enable diverse techniques.
A guide to find the right column for your characterization workflow. It includes advice and tips on method development, solvent choice, mobile phase modification, optimization, example separations, as well as ordering information.