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由于壽命很短，且具有良好的基因工具，秀麗隱桿線蟲一直是研究衰老的理想模型。但是，其他的生化研究工具卻發(fā)展緩慢，難以實(shí)現(xiàn)完整的生理診斷檢查。我們采用熱量限制突變體 eat-2、線粒體突變體 mev-1（琥珀酸脫氫酶）和 cco-1（細(xì)胞色素 c 氧化酶）等多樣化的遺傳模式，以及藥物干擾方法，建立了一系...