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Direct Analysis of In-Process Oligonucleotides Without Manual Purification (PDF)

Direct 2D-LC analysis of oligonucleotides in solution with high salt content, with online desalting in the first dimension and IP-RPLC in the second dimension.

  • 文件出版號: 5991-9490EN
  • 創(chuàng)建日期: 14 十月 2024
  • 912 KB
  • PDF
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Rapid Analysis of mRNA 5' Capping with High Resolution LC/MS (PDF)

Rapid mRNA capping analysis with a combined sample preparation and analysis time of only 75 minutes using an Agilent 6545XT AdvanceBio LC/Q-TOF.

  • 文件出版號: 5994-3984EN
  • 創(chuàng)建日期: 21 九月 2021
  • 1 MB
  • PDF
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Purification of Single-Stranded RNA Oligonucleotides Using High-Performance Liquid Chromatography (PDF)

This application note demonstrates the purification workflow of a single-stranded RNA ON by ion-pair reversed-phase HPLC.

  • 文件出版號: 5994-3514EN
  • 創(chuàng)建日期: 06 五月 2021
  • 365 KB
  • PDF
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Evaluation of Different Ion Pairing Reagents for LC/UV and LC/MS Analysis of Oligonucleotides (PDF)

This application note shows that there are numerous variables available for optimization of the analytical conditions for oligonucleotides. The analyses were carried out on an Agilent 1290 Infinity II LC System with UV detection by DAD and an...

  • 文件出版號: 5994-2957EN
  • 創(chuàng)建日期: 04 一月 2021
  • 806 KB
  • PDF
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Fast and High-Resolution Reversed-Phase Separation of Synthetic Oligonucleotides (PDF)

AdvanceBio Oligonucleotide with UV and MS eluents is ideal for oligonucleotides, with exceptional resolution, superior lifetime, compatible with 600 and 1200 bar.

  • 文件出版號: 5991-6006EN
  • 創(chuàng)建日期: 25 六月 2015
  • 330 KB
  • PDF

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