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應(yīng)用
利用 Agilent 6545XT AdvanceBio LC/Q-TOF 精確表征完整單克隆抗體 (PDF)

本應(yīng)用摘要提供了一套完整的高通量工作流程解決方案，可應(yīng)對各種 mAb 產(chǎn)品的分析。

  • 文件出版號: 5991-7813CHCN
  • 創(chuàng)建日期: 24 三月 2017
  • 785 KB
  • PDF
英語 (美國) 完整版（PDF）
應(yīng)用
使用 Agilent 6530 Q-TOF 對單克隆抗體藥物的二硫鍵連接進(jìn)行確認(rèn) (PDF)

本文介紹了使用 Agilent 6530 Q-TOF 采集肽段數(shù)據(jù)， 采用整合有 BioConfirm 的 MassHunter 定性軟件，通過軟件中的蛋白酶解產(chǎn)物比較功能，實(shí)現(xiàn)了對單克隆抗體藥物中二硫鍵連接的確證。此方法無需對樣品進(jìn)行額外的標(biāo)記，僅通過對還原和非還原組樣品的一級質(zhì)譜進(jìn)行比對，即可實(shí)...

  • 文件出版號: 5991-6068CHCN
  • 創(chuàng)建日期: 10 七月 2015
  • 628 KB
  • PDF
手冊
Innovation That Drives Breakthroughs in Biopharma - Agilent 6545XT AdvanceBio LC/Q-TOF System (PDF)

Ultimate flexibility for more informed decisions. One instrument and multiple workflows for biopharma.

  • 文件出版號: 5991-7915EN
  • 創(chuàng)建日期: 28 六月 2024
  • 26 MB
  • PDF
應(yīng)用
Critical Quality Attribute Monitoring of mAbs at the Intact and Subunit Levels Using a Cost-Effective, Simple and Robust LC/MS Solution (PDF)

Critical Quality Attribute Monitoring of mAbs at the Intact and Subunit Levels

  • 文件出版號: 5994-1349EN
  • 創(chuàng)建日期: 06 十二月 2019
  • 611 KB
  • PDF
應(yīng)用
Profiling Glycosylation of Monoclonal Antibodies at Three Levels Using the Agilent 6545XT AdvanceBio LC/Q-TOF (PDF)

This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.

  • 文件出版號: 5991-8796EN
  • 創(chuàng)建日期: 22 一月 2018
  • 1 MB
  • PDF
應(yīng)用
Analysis of Antibody Drug Conjugates Using SEC and Mass Spectrometry (PDF)

Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)

  • 文件出版號: 5991-6439EN
  • 創(chuàng)建日期: 01 十二月 2015
  • 1 MB
  • PDF

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