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本應用簡報為使用 XF 線粒體毒性檢測進行化合物篩選和劑量響應實驗以及使用線粒 體毒性指標 (MTI) 解析結果數(shù)據(jù)提供了概念驗證和示例。
| 英語 (美國) | 完整版（PDF） |
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| 英語 (美國) | 完整版（PDF） |
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The invasion of the 3D spheroid in the presence or absence of drug treatment was monitored and quantified using the brightfield and fluorescence live cell time-lapse
Specification data sheet for the Agilent xCELLigence Real-Time Cell Analyzer HT-Biotek BioSpa 8.
A protocol for mitocondrial isolation and oxygen consumption analysis using the Agilent MitoXpress Xtra oxygen consumption assay.
Noninvasive and continuous monitoring of the perturbation of cellular growth following exposure to the cumulative toxicants present in water samples.
A demonstration of combining microelectrode-based iPS cardiomyocyte contractility measurements with microplate-based bioenergetics assessment to characterize cellular responses to drug treatment.
Two Workflows: A Streamlined 384-well workflow to detect direct drug-induced mitochondrial dysfunction and Multiplexed workflow to detect mitochondrial toxicity after longer treatments
A demonstration of the performance of the Agilent MitoXpress Xtra oxygen consumption assay for identifying drug induced mitocondrial toxicity.
Multiplexed Screening of Drug-Induced Mitochondrial Dysfunction and Cytotoxicity
Screening for Drug-Induced Mitochondrial Dysfunction Using MitoXpress Xtra on Isolated Mitochondria
Poster - Cell-based Screening of Drug-Induced Metabolic Dysfunction
This poster Demonstrates the utility of Agilent Seahorse XF Real-Time ATP Rate Assay Kit and PMP in testing compound tox and understanding mechanism.