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Research highlight confirming the critical role of metabolic fitness in CAR-NK cells and its importance to achieve superior clinical outcomes in immunotherapy.
A protocol for mitocondrial isolation and oxygen consumption analysis using the Agilent MitoXpress Xtra oxygen consumption assay.
This document is an information guide and checklist prepared for you that outlines the supplies, space, and utility requirements for the system set up in your lab.
This application note introduces a workflow that uses the XF Real-Time ATP rate assay data for identifying metabolic modulator and drug targets.
Comprising instruments, assay kits, software, and consumables, Agilent Seahorse XF platforms are designed to support you from sample to insight.
Case study about CAR-T therapy
An overview of the features of the XF HS miniplate including how it accommodates smaller sample sizes and how this reduction relates to the underlying sensitivity improvements.
A demonstration of combining microelectrode-based iPS cardiomyocyte contractility measurements with microplate-based bioenergetics assessment to characterize cellular responses to drug treatment.
Characterize metabolic functionality of adipocytes differentiated from the pre-adipocyte 3Y3-L1 cell culture line using the Agilent Seahorse XF/XFe Analyzer.
Two workflows using MitoXpress Xtra and pH-Xtra probes to investigate cell metabolism in intact RAFT 3D collagen structures on fluorescent plate readers.
Two Workflows: A Streamlined 384-well workflow to detect direct drug-induced mitochondrial dysfunction and Multiplexed workflow to detect mitochondrial toxicity after longer treatments
User guide for the MitoXpress Xtra Oxygen Consumption Assay kit. Includes workflow, plate reader-, storage conditions and signal optimization instructions.
A demonstration of the performance of the Agilent MitoXpress Xtra oxygen consumption assay for identifying drug induced mitocondrial toxicity.
Multiplexed Screening of Drug-Induced Mitochondrial Dysfunction and Cytotoxicity
Screening for Drug-Induced Mitochondrial Dysfunction Using MitoXpress Xtra on Isolated Mitochondria
Correlating Microbial Proliferation with Antibiotic Resistance using the MitoXpress Xtra Oxygen Consumption Assay
The Agilent Bravo Seahorse Assay Workbench is a workflow solution for sample preparation of live-cell samples for analysis on an Agilent Seahorse XFe96 Analyzer
Poster - Cell-based Screening of Drug-Induced Metabolic Dysfunction
This poster Demonstrates the utility of Agilent Seahorse XF Real-Time ATP Rate Assay Kit and PMP in testing compound tox and understanding mechanism.
Protocol to assess primary whole islet bioenergetics in vitro using the Agilent Seahorse XF24 Islet Capture Microplate.